Skip to content
Center of
Trial & Error

Article type

Articles

This journal is no longer updated. Its articles stay available here as an archive.

2 articles

All articles
Articles

Kinin B1 receptor is involved in mechanical nociception in a fibromyalgia-like model in mice

Ana Paula Aquistapase Dagnino, Vanessa Machado Azevedo, Patricia Oliboni, Maria Martha Campos & Izaque de Sousa Maciel

Fibromyalgia-like models in mice induced by reserpine have opened a new avenue to understanding the molecular mechanisms behind this complex and incapacitating pain syndrome. The kinin B1 receptor (B1R) contributes to mechanical allodynia and acute coping behavior in mice with inflammatory and…

Read
Articles

Anticompulsive-like effect of nitric oxide synthase inhibitors in marble-burying test

Karina Montezuma, Caroline Biojone, Samia Joca, Plinio Casarotto & Francisco Silveira Guimarães

Nitric oxide synthase (NOS) inhibitors decrease marble burying behavior (MBB), and the effect of several compounds that also attenuate MBB (such as classical antidepressants) engages the nitrergic system. In the present study, we tested the effect of the NOS inhibitor aminoguanidine (AMG) in…

Read